ホーム > 研究業績
原著論文
2018年
- Matsumura K, Imai H, Go Y, Kusuhara M, Yamaguchi K, Shirai T, Ohshima K. Transcriptional activation of a chimeric retrogene PIPSL in a hominoid ancestor. Gene 678 (2018) 318-323, PMID:30096459
- Hayakawa T, Nathan SKSS, Stark DJ, Saldivar DAR, Sipangkui R, Goossens B, Tuuga A, Clauss M, Sawada A, Fukuda S, Imai H, Matsuda I. First report of foregut microbial community in proboscis monkeys: are diverse forests a reservoir for diverse microbiomes? Environ Microbiol Rep. 2018, PMID:29992728
- Katayama K, Furutani Y, Iwaki M, Fukuda T, Imai H, Kandori H (2018) "In situ" observation of the role of chloride ion binding to monkey green sensitive visual pigment by ATR-FTIR spectroscopy. Phys. Chem. Chem. Phys., 2018,20, 3381-3387, PMID:29297909
- Emiko Nishi, Nami Suzuki-Hashido, Takashi Hayakawa, Yamato Tsuji, Bambang Suryobroto, Hiroo Imai. Functional decline of sweet taste sensitivity of colobine monkeys. Primates (2018) PMID: 30191350
- Risako Nakai, Mari Ohnuki, Kota Kuroki, Haruka Ito, Hirohisa Hirai, Ryunosuke Kitajima, Toko Fujimoto, Masato Nakagawa, Wolfgang Enard, Masanori Imamura. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata). Scientific Reports 8(1): 12187 (2018). PMID: 30111816
- Nishihara H, Stanyon R, Kusumi J, Hirai H, Koga A (2018) Evolutionary origin of OwlRep, a megasatellite DNA associated with adaptation of owl monkeys to nocturnal lifestyle. Genome Biology and Evolution,10 (1): 157-165. PMID: 29294004
2017年
- Jung YD, Lee HE, Jo A, Hiroo I, Cha HJ, Kim HS. Activity analysis of LTR12C as an effective regulatory element of the RAE1 gene. Gene 634 (2017) 22-28, PMID:28867566
- Anthony J Tosi, Hirohisa Hirai (2017) X chromosome introgression and recombination in the cephus group of Cercopithecus monkeys. Cytogenet Genome Res, PMID: 28977788
- Shoji Tatsumoto, Yasuhiro Go, Kentaro Fukuta, Hideki Noguchi, Takashi Hayakawa, Masaki Tomonaga, Hirohisa Hirai, Tetsuro Matsuzawa, Kiyokazu Agata and Asao Fujiyama (2017). Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing. Scientific Reports, 7, 13561. PMID:29093469
- K. Katayama, Y. Nonaka, K. Tsutsui, H. Imai, H. Kandori. (2017) Spectral Tuning Mechanism of Primate Blue-Sensitive Visual Pigment Elucidated by FTIR Spectroscopy. Sci. Rep 7, 4904. PMID: 28687791
- K. Fukuda, Y. Inoguchi, K. Ichiyanagi, T. Ichiyanagi, Y. Go, M. Nagano, Y, Yanagawa, N. Takaesu, Y. Ohkawa, H. Imai, H. Sasaki (2017) Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability. Hum Mol Genet. 26, 3508-3519. PMID:28637190
- Y. Terai, R. Miyagi, M. Aibara, S. Mizoiri, H. Imai, T. Okitsu, A. Wada, S. Takahashi-Kariyazono, A. Sato, H. Tichy, H. Mrosso, S. Mzighani, N. Okada (2017) Visual adaptation in Lake Victoria cichlid fishes: depth-related variation of color and scotopic opsins in species from sand/mud bottoms BMC Evolutionary Biology 17, 200 DOI:10.1186/s12862-017-1040
- Akihiko Koga, Hideyuki Tanabe, Yuriko Hirai, Hiroo Imai, Masanori Imamura, Takao Oishi, Roscoe Stanyon, Hirohisa Hirai. Co-Opted Megasatellite DNA Drives Evolution of Secondary Night Vision in Azara’s OwlMonkey. Genome Biology and Evolution 9(7): 1963-1970 (2017) PMID: 28810713
- Hirata S, Hirai H, Nogami E, Morimura N, Udono T (2017) Chimpanzee down syndrome: a case study of trisomy 22 in a captive chimpanzee. Primates, 58:267-273. PMID:28220267
- Hirohisa Hirai, Yuriko Hirai, Mayumi Morimoto, Akihisa Kanoko, Yoshiro Kamanaka, Akihiko Kokga (2017) Night monkey hybrids exhibit de novo genomic and karyotypic alterations: the first such case in primates. Genome Biology and Evolution PMID: 28369492
- S. Bunlungsup, H. Imai, Y. Hamada, K. Matsudaira, S. Malaivijitnond. Mitochondrial DNA and two Y-chromosome genes of common long-tailed macaques (Macaca fascicularis fascicularis) throughout Thailand and vicinity. Am J Primatol 79, e22596 PMID: 27643851
- L. H. P. Purba, K. A. Widayati, K. Tsutsui, N. Suzuki-Hashido, T. Hayakawa, S. Nila, B. Suryobroto, H. Imai. Functional characterization of the TAS2R38 bitter taste receptor for phenylthiocarbamide in colobine monkeys. Biology Letters 13, 20160834. PMID: 28123110
2016年
- Sudarath Baicharoen, Yuriko Hirai, Kornsorn Srikulnath, Urarikha Kongprom, Hirohisa Hirai(2016) Hypervariability of nucleolus organizer regions in Bengal slow lorises, Nycticebus bengalensis (Primates, Lorisidae). Cytogenetic and Genome Research, July 11, 2016 PMID: 27648559
- E. Nishi, K. Tsutsui, H. Imai. High maltose sensitivity of sweet taste receptors in the Japanese macaque (Macaca fuscata). Scientific Reports 6, Article number: 39352 PMID: 27982108
- K. Tsutsui, M. Otoh, K. Sakurai, N. Suzuki-Hashido, T. Hayakawa, T. Misaka, Y. Ishimaru, F. Aureli, A. D. Melin, *S. Kawamura, *H. Imai. Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys. BMC Evolutionary Biology 16:208. DOI: 10.1186/s12862-016-0783-0
- S. Kawamura, S. Kasagi, D. Kasai, A. Tezuka, A. Shoji, A. Takahashi, H. Imai, M. Kawata Spectral sensitivity of guppy visual pigments reconstituted in vitro to resolve association of opsins with cone cell types. Vision Research 127 67-73 PMID: 27476645
- K. Yoshida, Y. Go, I. Kushima, A. Toyoda, A. Fujiyama, H. Imai, N. Saito, A. Iriki, N. Ozaki, M. Isoda Single-neuron and genetic correlates of autistic behavior in macaque Science Advances 2, e1600558 PMID: 27679817
- H. Imai, N. Suzuki-Hashido, Y. Ishimaru, T. Sakurai, L. Yin, W. Pan, M. Ishiguro, K. Masuda, K. Abe, T. Misaka, and H. Hirai. Amino acid residues of bitter taste receptor TAS2R16 that determine sensitivity in primates to b-glycosides. Biophysics and Physicobiology 13: 165-171. DOI: 10.2142/biophysico.13.0_165
- S. Bunlungsup, H. Imai, Y. Hamada, M.D. Gumert, A.M. San, and S. Malaivijitnond. Morphological characteristics and genetic diversity of Burmese long-tailed Macaques (Macaca fascicularis aurea). American Journal of Primatology 78: 441-455. PMID: 26670099
- Francesco Nicola Carelli, Takashi Hayakawa, Yasuhiro Go, Hiroo Imai, Maria Warnefors and Henrik Kaessmann. The life history of retrocopies illuminates the evolution of new mammalian genes. Genome Research 26, 301-314. PMID: 26728716
- Zachary Yu-Ching Lin, Orie Hikabe, Sadafumi Suzuki, Takamasa Hirano, Haruhiko Siomi, Erika Sasaki, *Masanori Imamura, *Hideyuki Okano. Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey. Primates 57(1): 129-35. PMID: 26530217
2015年
- K. Katayama, T. Okitsu, H. Imai, A. Wada, and H. Kandori. Identical Hydrogen-Bonding Strength of the Retinal Schiff Base between Primate Green- and Red-Sensitive Pigments: New Insight into Color Tuning Mechanism. J Phys Chem Lett. 6, 1130-1133. PMID: 26262961
- Nami Suzuki-Hashido, Takashi Hayakawa, Atsushi Matsui, Yasuhiro Go, Yoshiro Ishimaru, Takumi Misaka, Keiko Abe, Hirohisa Hirai, Yoko Satta, Hiroo Imai . Rapid Expansion of Phenylthiocarbamide Non-Tasters among Japanese Macaques.PLoS One 10(7): e0132016. DOI: 10.1371/journal.pone.013201
- Penporn Sujiwattanarat, Watcharaporn Thapana, Kornsorn Srikulnath, Yuriko Hirai, Hirohisa Hirai & Akihiko Koga. Higher-order repeat structure in alpha satellite DNA occurs in New World monkeys and is not confined to hominoids. Scientific Reports 5: 10315. PMID: 25974220
- Rokusuke Yoishikawa, Munehiro Okamoto, Shoichi Sakaguchi, So Nakagawa, Tomoyuki Miura, Hirohisa Hirai, Takayuki Miyazawa. Simian retrovirous 4 induces lethal acute thrombocytopenia in Japanese macaques. Journal of Virology 89(7): 3965-3975. PMID: 25609821
- Zachary Yu-Ching Lin, Takamasa Hirano, Shinsuke Shibata, Naomi M. Seki, Ryunosuke Kitajima, Ayako Sedohara, Mikiko C. Siomi, Erika Sasaki, Haruhiko Siomi, Masanori Imamura, Hideyuki Okano. Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development. Developmental Biology 400(1): 43-58. PMID: 25624265
- Okamoto M, Miyazawa T, Morikawa S, Ono F, Nakamura S, Sato E, Yoshida T, Yoshikawa R, Sakai K, Mizutani T, Nagata N, Takano J, Okabayashi S, Hamano M, Fujimoto K, Nakaya T, Iida T, Horri T, Miyabe-Nishiwaki T, Watanabe A, Kaneko A, Saito A, Matsui A, Hayakawa T, Suzuki J, Akari H, Matsuzawa T, Hirai H. Emergence of infectious malignant thrombocytopenia in Japanese macaques (Macaca fuscata) by SRV-4 after transmission to a novel host. Scientific Reports 5: 8850. PMID: 25743183
- T. Kishida, JGM Thewissen, T. Hayakawa, H. Imai and K. Agata. Aquatic adaptation and the evolution of smell and taste in whales. Zoological Letters 1: 9. doi:10.1186/s40851-014-0002-z
2014年
- Thapana W, Sujiwattanarat P, Srikulnath K, Hirai H, Koga A. Reduction in the structural instability of cloned eukaryotic tandem-repeat DNA by low-temperature culturing of host bacteria. Genetics Resarch 96: e13. 25578068
- Yuri Choi, Yi-Deun Jung, Selvam Ayarpadikannan, Akihiko Koga, Hiroo Imai, Hirohisa Hirai, Christian Roos,and Heui-Soo Kim. Novel variable number of tandem repeats of gibbon MAOA gene and its evolutionary significance. Genome 57(8): 427-432. PMID: 25360715
- Takao Oishi, Hiroo Imai, Yasuhiro Go, Masanori Imamura, Hirohisa Hirai, Masahiko Takada. Sporadic premature aging in a Japanese monkey: a primate model for progeria. PLoS One 9:10 e111867. PMID: 25365557
- Sudarasth Bicharoen, Takako Miyabe-Nishjiwaki, Visit Arsaithamkul, Yuriko Hirai, Kwanruen Duangsa-ard, Boripat Siriaroonrat, Hiroshi Domae, Kornsorn Srikulnath, Akihiko Koga, Hirohisa Hirai .Locational diversity of alpha satellite DNA and intergeneric hybridization aspects in the Nomascus and Hylobates genera of small apes. PLoS One 9:10 e109151. PMID: 25290445
- Hirohisa Hirai. (2014) Chromosomal differentiation of schistosomes: what is the message? frontiers in GENETICS 5: 301. doi: 10.3389/fgene.2014.00301
- Jungwoo Eo, Hee-Jae Cha, Hiroo Imai, Hirohisa Hirai, Heui-Soo Kim. (2014) Expression Profiles of Endogenous Retroviral Envelopes in Macaca Mulatta (Rhesus Monkey). AIDS Research and Human Retroviruses 30: 996-1000. PMID: 24961963
- Takashi Hayakawa, Nami Suzuki-Hashido, Atsushi Matsui, Yasuhiro Go. (2014) Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade. Molecular Biology and Evolution 31: 2018-2031. PMID: 24758778
- Hirano T, Iwasaki YW, Lin ZY, Imamura M, Seki NM, Sasaki E, Saito K, Okano H, Siomi MC, Siomi H. (2014) Small RNA profiling and characterization of piRNA clusters in the adult testes of the common marmoset, a model primate. RNA 20: 1223-1237. PMID: 24914035
- Naka I, Patarapotikul J, Hananantachai H, Imai H, Ohashi J. (2014) Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria. Malar J. 13, 105 PMID:24635948
- Imamura M, Hikabe O, Lin ZY, Okano H. (2014) Generation of Germ Cells In Vitro in the Era of Induced Pluripotent Stem Cells. Molecular Reproduction and Development 81: 2-19. PMID:23996404
総説
- 今井啓雄，林美沙 (2018) 動物の感覚とヒトとの比較. 「ひと・健康・未来 18 (2018)」
- 今井啓雄 (2017) 味覚受容体の進化と多様性. アグリバイオ 1, 89-91.
- 橋戸（鈴木）南美 (2016) 遺伝子からわかるサルの味覚「なきごえ」52: 3
- 今井啓雄，西栄美子 (2016) 味覚受容体タンパク質の進化と多様性「生物科学」67: 75-84
- 今井啓雄 (2015) サルの味覚を追ってフィールドに。「フィールドプラス」15: 22-23.
- 筒井圭, 今井啓雄 (2015)霊長類苦味受容体の機能的多様性 「比較生理生化学」32: 24-29.
- Imamura M, Hikabe O, Lin ZY, Okano H. (2014) Generation of Germ Cells In Vitro in the Era of Induced Pluripotent Stem Cells. Molecular Reproduction and Development 81: 2-19. PMID:23996404
- 今井啓雄，筒井圭 (2013) 霊長類苦味受容体の多様化「生体の科学」64: 430-431
- 早川卓志，今井啓雄 (2013) チンパンジーにおける苦味感覚の地域差と進化「生物の科学 遺伝」67: 418-424
- 今井啓雄，鈴木南美 (2013) 生息環境に応じた感覚受容体の機能進化「生物物理」53: 194-197. 日本生物物理学会
出版物
2016年
- 鈴木-橋戸南美, 今井啓雄 霊長類の味覚 「 おいしさの科学的評価・測定法と応用展開」（シーエムシー出版）p.22-33.分担執筆
- 今井啓雄 (2016) 昼間視（明所視） 「光と生命の事典」（朝倉書店）p.238-239.分担執筆
2013年
- Y. Shichida, T. Yamashita, H. Imai, T. Kishida (2013) Evolution and Senses: Opsins, Bitter Taste, Olfaction.
編集
- Hirai H, Imai H and Go Y (2012) Post-Genome Biology of primates, Primatology Monographs, Springer
