Context-dependent representation of reinforcement in monkey amygdala
Hirai, Daichi; Hosokawa, Takayuki; Inoue, Masato; Miyachi, Shigehiro; Mikami, Akichika
It has been reported that neurons in the amygdala respond to visual cues
that predict reward and aversive outcomes. However, it remains unclear
whether the representation of reinforcement in the amygdala depends on the
relative preference for an outcome compared with another simultaneously
available outcome. In this study, we introduced three reinforcements
(juice, water, and electrical stimulus) and used two of them in one
experimental block. Of 52 neurons that showed cue responses reflecting the
outcome information, 23% of amygdala neurons coded preferred outcomes,
whereas only one neuron coded nonpreferred outcomes. These proportions of
amygdala were significantly different from those of the orbitofrontal
cortex, which had both types of neurons.
NeuroReport. 20(6):558-562, 2009.APR/20/2009
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