統合脳システム分野

研究業績 ~Publications~


2017

Ichinose H, Inoue K, Arakawa S, Watanabe Y, Kurosaki H, Koshiba S, Hustad E, Takada M, Aasly JO, (2017) Alterations in the reduced pteridine contents in the cerebrospinal fluids of LRRK2 mutation carriers and patients with Parkinson's disease. J Neural Transm, in press.

Oh Y-M, Karube F, Takahashi S, Kobayashi K, Takada M, Uchigashima M, Watanabe M, Nishizawa K, Kobayashi K, Fujiyama F, (2017) Using a novel PV-Cre ratmodel to characterize pallidonigral cells and their terminations. BrainStruct Funct, 222:2359-2378.

Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Wascheck JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K. Baba A, Hashimoto H, (2017) High-speed and scalable whole-brain imaging in rodents and primates. Neuron, 94:1085-1100.

Tanabe S, Inoue K, Tsuge H, Uezono S, Nagaya K, Fijiwara M, Kato S, Kobayashi K, Takada M (2017) The use of an optimized chimeric envelope glycoprotein enhances the efficiency of retrograde gene transfer of a pseudotyped lentiviral vector in the primate brain. Neurosci Res, 120:45-52.

Saga Y, Nakayama Y, Inoue K,Ymagata T, Hashimoto M, Tremblay L ,Takada M,Hoshi E (2017) Visuomotor signals for reaching movements in the rostro-dorsal sector of the monkey thalamic reticular nucleus. Eur J Neurosci, 45:1186-1199.



2016

Nagai Y, Kikuchi E, Lerchner W, Inoue K, Ji B, Eldridge MAG, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang M-R, Aoki I, Suhara T, Higuchi M, Takada M, Richmond BJ, Minamimoto T (2016) PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation. Nat Commun, 7:13605.

Kimura K, Inoue K, Kuroiwa Y, Ynaka F, Takada M (2016) Propagated butTopologically Distributed Forebrain Neurons Expressing Alpha-Synuclein in Aged Macaque. PLoS ONE, 11, e0166861.



2015

McCairn KW, Nagai Y, Hori Y, Ninomiya T, Kikuchi E, Lee J-Y, Suhara T, Iriki A, Minamimoto T, Takada M, Isoda M, Matsumoto M (2015) A primary role for nucleus accumbens and related limbic network in vocal tics. Neuron, 89:300-307.

Ishida H, Inoue K, Takada M, Hoshi E (2015) Origins of multisynaptic projections from the basal ganglia to the forelimb region of the ventral premotor cortex in macaque monkeys. Eur J Neurosci, 43:258-269.

Kawai T, Yamada H, Sato N, Takada M, Matsumoto M (2015) Roles of the lateral habenula and anterior cingulate cortex in negative outcome monitoring and behavioral adjustment in nonhuman primates. Neuron, 88:792-804.

Ito T, Inoue K, Takada M (2015) Distributions of glutamatergic, GABAergic, and glycinergic neurons in the auditory pathways of macaque monkeys. Neuroscience, 310:128-151.

Inoue K, Takada M, Matsumoto M (2015) Neuronal and behavioral modulations by pathway-selective optogenetic stimulation of the primate oculomotor system. Nat Commun, 6:8378.

Nakagawa H, Ninomiya T, Yamashita T, Takada M (2015) Reorganization of corticospinal tract fibers after spinal cord injury in adult macaques. Sci Rep 5:11986.

Chung G, Saito M, Kawano T, Lee S, Takada M, Bae Y.C, Oh S.B, Kang Y (2015) Generation of resonance-dependent oscillation by mGluR-I activation switches single spiking to bursting in mesencephalic trigeminal sensory neurons. Eur J Neurosci, 41:998-1012.

Hiraoka M, Inoue K, Senoo H, Takada M (2015) Morphological study of the accommodative apparatus in the monkey eye. Anat Rec, 298:630-636.

Murata Y, Higo N, Oishi T, Isa T (2015) Increased expression of the growth-associated protein-43 gene after primary motor cortex lesion in macaque monkeys. Neuroscience Research, 98:64-69.

Murata Y, Higo N, Hayashi T, Nishimura Y, Sugiyama Y, Oishi T, Tsukada H, Isa T, Onoe H (2015) Temporal plasticity involved in recovery from manual dexterity deficit after motor cortex lesion in macaque monkeys. Journal of Neuroscience, 35:84-95.



2014

Oishi T, Imai H, Go Y, Imamura M, Hirai H, Takada M (2014) Sporadic premature aging in a Japanese monkey: a primate model for progeria. PLoS ONE, e111867.

Tohno Y, Tohno S, Oishi T, Minami T, Khanpetch P, Azuma C, Quiggins R (2014) Age-related decrease of the phosphorus content in the ligamentum capitis femoris of monkeys. Biological Trace Element Research, 161:78-84.



2013

Yoshida T, Suzuki S, Iwasaki Y, Kaneko A, Saito A, Enomoto Y, Higashino A, Watanabe A, Suzuki J, Inoue K, Kuroda T, Takada M, Ito R, Ito M, Akari H (2013) Efficient in vivo depletion of CD8+ T lymphocytes in common marmosets by novel CD8 monoclonal antibody administration. Immunol Lett, 154:12-17.

Hirata Y, Miyachi S, Inoue K, Ninomiya T, Takahara D, Hoshi E, Takada M (2013) Dorsal area 46 is a major target of disynaptic projections from the medial temporal lobe. Cereb Cortex, 23:2965-2975.

Hayashizaki S, Hirai S, Ito Y, Honda Y, Arime Y, Sora I, Okado H, Kodama T, Takada M (2013) Methamphetamine increases locomotion and dopamine transporter activity in dopamine D5 receptor-deficient mice. PLoS ONE,8:e75975.

Matsumoto M, Takada M (2013) Distinct representations of cognitive and motivational signals in midbraindopamine neurons. Neuron, 79:1011-1024.

Isomura Y, Takekawa T, Harukuni R, Handa T, Aizawa H, Takada M, Fukai T (2013) Reward-modulated motor information in identified striatum neurons. J Neurosci, 33:10209-10220.

Hayakawa H, Nagai M, Kawanami A, Nakata Y, Nihira T, Ogino M, Takada M, Saido T, Takano J, Saegusa M, Mikami T, Hamada J, Nishiyama K, Mochizuki H, Mizuno Y (2013) Loss of DARPP-32 and calbindin in multiple system atrophy. J Neural Transm, 120:1689-1698.

Hoshina N, Tanimura A, Yamasaki M, Inoue T, Fukabori R, Kuroda T, Yokoyama K, Tezuka T, Sagara H, Hirano S, Kiyonari H, Takada M, Kobayashi K, Watanabe M, Kano M, Nakazawa T, Yamamoto T (2013) Protocadherin 17 regulates presynaptic assembly in topographic cortico-basal ganglia circuits. Neuron, 78:839-854.

Miyachi S, Hirata Y, Inoue K, Lu X, Nambu A, Takada M (2013) Multisynaptic projections from the ventrolateral prefrontal cortex to hand and mouth representations of the monkey primary motor cortex. Neurosci Res, 76:141-149.

Hiraoka M, Kuroda T, Inoue K, Senoo H, Takada M (2013) Developmental anatomy in the zonular connection with lens capsule in macaque eye. Anat Rec, 295:347-54.

Sugiyama Y, Higo N, Yoshino-Saito K, Murata Y, Nishimura Y, Oishi T, Isa T (2013) Effects of early versus late rehabilitative training on manual dexterity after corticospinal tract lesion in macaque monkeys. Journal of Neurophysiology, 109:2853-2865.

Yamamoto T, Oishi T, Higo N, Murayama S, Sato A, Takashima I, Sugiyama Y, Nishimura Y, Murata Y, Yoshino-Saito K, Isa T, Kojima T (2013) Differential Expression of Secreted Phosphoprotein 1 in the Motor Cortex among Primate Species and during Postnatal Development and Functional Recovery. PLoS ONE, 8:e65701.

Kojima T, Higo N, Sato A, Oishi T, Nishimura Y, Yamamoto T,Murata Y, Yoshino-Saito K, Onoe H, Isa T (2013) Functional annotation of genes differentially expressed between primary motor and prefrontal association cortices of macaque brain. Neurochemical Research, 38:133-140.



2012

Ninomiya T, Sawamura H, Inoue K,Takada M (2012) Multisynaptic inputs from the medial temporal lobe to V4 in macaques. PLoS ONE , 7:e52115.

Lu X, Miyachi S, Takada M (2012) Anatomical evidence for the involvement of medial cerebellar output from the interpositus nuclei in cognitive functions. Proc Natl Acad Sci USA , 109:18980-18984.

Takahara D, Inoue K, Hirata Y, Miyachi S, Nambu A, Takada M, Hoshi E (2012) Multisynaptic projections from the ventrolateral prefrontal cortex to the dorsal premotor cortex in macaques: anatomical substrate for conditional visuomotor behavior. Eur J Neurosci , 36: 3365-3375.

Inoue K, Koketsu D, Kato S, Kobayashi K, Nambu A, Takada M (2012) Immunotoxin-mediated tract targeting in the primate brain: selective elimination of the cortico-subthalamic ”hyperdirect” pathway. PLoS ONE , 7:e39149.

Ninomiya T, Sawamura H, Inoue K, Takada M (2012) Segregated pathways carrying frontally derived top-down signals to visual areas MT and V4 in macaques. J Neurosci, 32:6851-6858.

Hiraoka M, Inoue K, Ninomiya T, Takada M (2012) Ischaemia in the Zinn-Haller circle and glaucomatous optic neuropathy in macaque monkeys. Br J Ophthalmol , 96:597-603.

Hiraoka M, Inoue K, Kawano H, Takada M (2012) Localization of papillofoveal bundles in primates. Anat Rec ,295:347-354.

Shimizu J, Fukuda T, Abe T, Ogihara M, Kubota J,Sasaki A, Azuma T, Sasaki K, Shimizu K, Oishi T, Umemura S-I, Furuhata H (2012) Ultrasound Safety with Midfrequency Transcranial Sonothrombolysis: Preliminary Study on Normal Macaca Monkey Brain. Ultrasound in Medicine and Biology ,38:1040-1050.

Higaki S, Takumi K, Itoh M, Watanabe G, Taya K, Shimizu K, Hayashi M, Oishi T (2012) Response of ERβ and aromatase expression in the monkey hippocampal formation to ovariectomy and menopause. Neuroscience Research,72:148-154.



2011

Kato S, Kuramochi M, Takasumi K, Kobayashi K, Inoue K, Takahara D, Hitoshi S, Ikenaka K, Shimada T, Takada M, Kobayashi K (2011) Neuron-specific gene transfer through retrograde transport of lentiviral vector pseudotyped with a novel type of fusion envelope glycoprotein. Hum Gene Ther , 22:1511-1523.

Tachibana Y, Iwamuro H, Kita H, Takada M, Nambu A (2011) Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal ganglia. Eur J Neurosci , 34:1470-1484.

Masuda M, Miura M, Inoue R, Imanishi M, Saino-Saito S, Takada M, Kobayashi K, Aosaki T (2011) Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum. Eur J Neurosci , 34:1355-1367.

Takara S, Hatanaka N, Takada M, Nambu A (2011) Differential activity patterns of putaminal neurons with inputs from the primary motor cortex and supplementary motor area in behaving monkeys. J Neurophysiol , 106:1203-1217.

Yasuda T, Hayakawa H, Nihira T, Ren Y-R, Nagai M, Hattori N, Miyake K, Takada M, Shimada T, Mizuno Y, Mochizuki H (2011) Parkin-mediated dopaminergic neuroprotection in an MPTP-minipump mouse model of Parkinson's disease. J Neuropath Exp Neurol, 70:686-697.

Yumoto N, Lu X, Henry T, Miyachi S, Nambu A, Fukai T, Takada M (2011) A neural correlate of the processing of multi-second time intervals in primate prefrontal cortex. PLoS ONE, 6(4): e19168.

Ninomiya T, Sawamura H, Inoue K, Takada M (2011) Differential architecture of multisynaptic geniculo-cortical pathways to V4 and MT. Cereb Cortex, 21:2797-2808.

Matsumoto M, Hikosaka O (2011) Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism. PLoS ONE, 6: e26701.

Kato S, Kobayashi K, Inoue K, Kuramochi M, Okada T, Yaginuma H, Morimoto K, Shimada T, Takada M, Kobayashi K (2011) A lentiviral strategy for highly efficient retrograde gene transfer by pseudotyping with fusion envelope glycoprotein. Hum Gene Ther, 22(2):197-206.

Saga M, Hirata Y, Takahara D, Inoue K, Miyachi S, Nambu A, Tanji J, Takada M, Hoshi E (2011) Origins of multisynaptic projections from the basal ganglia to rostrocaudally distinct sectors of the dorsal premotor area in macaques. Eur. J. Neurosci, 33(2):285-297.

Iwata K, Miyachi S, Imanishi M, Tsuboi Y, Kitagawa J, Teramoto K, Hitomi S, Shinoda M, Kondo M, Takada M (2011) Ascending multisynaptic pathways from the trigeminal ganglion to the anterior cingulate cortex. Exp. Neurol, 227(1):69-78.

Tohno Y, Tohno S, Satoh H, Hayashi M, Oishi T, Minami T, Mahakkanukrauh P (2011) Gender differences in the phosphorus content of the sino-atrial nodes and other cardiac regions of monkeys. Biological Trace Element Research, 143,2,871-881.

Nagano M, Oishi T, Suzuki H (2011) Distribution and pharmacological characterization of primate NK-2 tachykinin receptor in the central nervous system of the rhesus monkey. Neuroscience Letters, 503,1,23-26.

Shinomiya K, Matsuda K, Oishi T, Otsuna H, Ito K (2011) Flybrain neuron database: A comprehensive database system of the Drosophila brain neurons. Journal of Comparative Neurology,519,5,807-833.

Yamamoto T, Higo N, Sato A, Nishimura Y, Oishi T, Murata Y, Yoshino-Saito K, Isa T, Kojima T (2011) SPP1 expression in spinal motor neurons of the macaque monkey. Neuroscience Research,69,1,81-86.



2010

Fujiwara-Tsukamoto Y, Isomura Y, Imanishi M, Ninomiya T, Tsukada M, Yanagawa Y, Fukai T, Takada M (2010) Prototypic seizure activity driven by mature hippocampal fast-spiking interneurons. J. Neurosci, 30:13679-13689.

Toyoda H, Saito M, Okazawa M, Hirao K, Sato H, Abe H, Takada K, Funabiki K, Takada M, Kaneko T, Kang Y (2010) Protein kinase G dynamically modulates TASK1-mediated leak K+ currents in cholinergic neurons of the basal forebrain. J. Neurosci, 30:5677-5689.

Hashimoto M, Takahara D, Hirata Y, Inoue K, Miyachi S, Nambu A, Tanji J, Takada M, Hoshi E (2010) Motor and nonmotor projections from the cerebellum to rostrocaudally distinct sectors of the dorsal premotor cortex in macaques. Eur. J. Neurosci, 31(8):1402-1413.

Higo N, Sato A, Yamamoto T, Nishimura Y, Oishi T, Murata Y, Onoe H, Yoshino-Saito K, Tsuboi F, Takahashi M, Isa T, Kojima T (2010) SPP1 is expressed in corticospinal neurons of the macaque sensorimotor cortex. Journal of Comparative Neurology, 518(13):2633-2644.

Satoh H, Tohno S, Minami T, Oishi T, Hayashi M, Tohno Y (2010) Gender-related differences in a process of the age-dependent alterations of the elements in monkey sino-atrial node. Korean Journal of Physiology & Pharmacology, 14(5):249-256.

Yoshino-Saito K, Nishimura Y, Oishi T, Isa T (2010) Quantitative inter-segmental and inter-laminar comparison of corticospinal projections from the forelimb area of the primary motor cortex of macaque monkeys. Neuroscience, 171(4):1164-1179.

Kaoru T, Liu FC, Ishida M, Oishi T, Hayashi M, Kitagawa M, Shimoda K, Takahashi H (2010) Molecular characterization of the intercalated cell masses of the amygdala: implications for the relationship with the striatum. Neuroscience, 166(1):220-230.

Tohno Y, Suwanahoy P, Tohno S, Sinthubua A, Azuma C, Nishiwaki F, Moriwake Y, Kumai T, Minami T, Laowatthanaphong S, Mahakkanukrauh P, Oishi T, Hayashi M (2010) Age-related changes of elements in the tendons of the peroneus longus muscles in Thai, Japanese, and monkeys. Biol Trace Elem Res, 133(3):291-303.

Ohira K, Furuta T, Hioki H, Nakamura KC, Kuramoto E, Tanaka Y, Funatsu N, Shimizu K, Oishi T, Hayashi M, Miyakawa T, Kaneko T, Nakamura S (2010) Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells. Nat Neurosci, 13(2):173-179.

Bromberg-Martin ES, Matsumoto M, Nakahara H, Hikosaka O (2010) Multiple timescales of memory in lateral habenula and dopamine neurons. Neuron, 67(3):499-510.

Bromberg-Martin ES, Matsumoto M, Hikosaka O (2010) Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons. Neuron, 67(1):144-155.

Bromberg-Martin ES, Matsumoto M, Hong S, Hikosaka O (2010) A pallidus-habenula-dopamine pathway signals inferred stimulus values. Journal of Neurophysiology, 104:1068-1076.